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Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York

Increased ambient air pollutant concentrations during pregnancy have been associated with reduced birth weight, but the etiologically relevant pregnancy time window(s) is/are unclear. In 76,500 singleton births in Monroe County, NY (2005–2016), who were 37–42 gestational weeks at delivery, we used g...

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Autores principales: Li, Rui, Hopke, Philip K., Dozier, Ann, Thurston, Sally W., Thevenet-Morrison, Kelly, Croft, Daniel, Masiol, Mauro, Squizzato, Stefania, Chalupa, David, Rich, David Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592743/
https://www.ncbi.nlm.nih.gov/pubmed/30940881
http://dx.doi.org/10.1038/s41370-019-0131-8
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author Li, Rui
Hopke, Philip K.
Dozier, Ann
Thurston, Sally W.
Thevenet-Morrison, Kelly
Croft, Daniel
Masiol, Mauro
Squizzato, Stefania
Chalupa, David
Rich, David Q.
author_facet Li, Rui
Hopke, Philip K.
Dozier, Ann
Thurston, Sally W.
Thevenet-Morrison, Kelly
Croft, Daniel
Masiol, Mauro
Squizzato, Stefania
Chalupa, David
Rich, David Q.
author_sort Li, Rui
collection PubMed
description Increased ambient air pollutant concentrations during pregnancy have been associated with reduced birth weight, but the etiologically relevant pregnancy time window(s) is/are unclear. In 76,500 singleton births in Monroe County, NY (2005–2016), who were 37–42 gestational weeks at delivery, we used generalized linear models to regress term birth weight against mean gestational month pollutant concentrations, adjusting for mean temperature, and maternal, infant, and medical service use characteristics. Overall, there were no clear patterns of term birth weight change associated with increased concentrations of any pollutant across gestational months. However, among Hispanic women only, increases in all pollutants, except O(3), in multiple gestational months, were associated with decreased term birth weight. Each 3.25 µg/m(3) increase in PM(2.5) concentration in the 6(th) gestational month was associated with a −20.4 g (95% CI = −34.0, −6.8) reduction in term birth weight among Hispanic women, but a 4.1 g (95% CI = −2.5, 10.8) increase among non-Hispanic mothers (p for interaction < 0.001). Although ambient air pollutant concentrations during pregnancy were not associated with reduced term birth weight among women of all ethnicities living in Monroe County, this observed association in Hispanic mothers may be a result of less exposure misclassification and bias (due to closer residential proximity to the monitoring site).
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spelling pubmed-65927432019-10-02 Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York Li, Rui Hopke, Philip K. Dozier, Ann Thurston, Sally W. Thevenet-Morrison, Kelly Croft, Daniel Masiol, Mauro Squizzato, Stefania Chalupa, David Rich, David Q. J Expo Sci Environ Epidemiol Article Increased ambient air pollutant concentrations during pregnancy have been associated with reduced birth weight, but the etiologically relevant pregnancy time window(s) is/are unclear. In 76,500 singleton births in Monroe County, NY (2005–2016), who were 37–42 gestational weeks at delivery, we used generalized linear models to regress term birth weight against mean gestational month pollutant concentrations, adjusting for mean temperature, and maternal, infant, and medical service use characteristics. Overall, there were no clear patterns of term birth weight change associated with increased concentrations of any pollutant across gestational months. However, among Hispanic women only, increases in all pollutants, except O(3), in multiple gestational months, were associated with decreased term birth weight. Each 3.25 µg/m(3) increase in PM(2.5) concentration in the 6(th) gestational month was associated with a −20.4 g (95% CI = −34.0, −6.8) reduction in term birth weight among Hispanic women, but a 4.1 g (95% CI = −2.5, 10.8) increase among non-Hispanic mothers (p for interaction < 0.001). Although ambient air pollutant concentrations during pregnancy were not associated with reduced term birth weight among women of all ethnicities living in Monroe County, this observed association in Hispanic mothers may be a result of less exposure misclassification and bias (due to closer residential proximity to the monitoring site). Nature Publishing Group US 2019-04-02 2019 /pmc/articles/PMC6592743/ /pubmed/30940881 http://dx.doi.org/10.1038/s41370-019-0131-8 Text en © Springer Nature America, Inc. 2019 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Li, Rui
Hopke, Philip K.
Dozier, Ann
Thurston, Sally W.
Thevenet-Morrison, Kelly
Croft, Daniel
Masiol, Mauro
Squizzato, Stefania
Chalupa, David
Rich, David Q.
Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title_full Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title_fullStr Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title_full_unstemmed Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title_short Term birth weight and ambient air pollutant concentrations during pregnancy, among women living in Monroe County, New York
title_sort term birth weight and ambient air pollutant concentrations during pregnancy, among women living in monroe county, new york
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592743/
https://www.ncbi.nlm.nih.gov/pubmed/30940881
http://dx.doi.org/10.1038/s41370-019-0131-8
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