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Thermal constraints on in vivo optogenetic manipulations
A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive. Commonly-used illumination protocols increased temperature by 0.2–2°C and suppressed spiking in multiple br...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592769/ https://www.ncbi.nlm.nih.gov/pubmed/31209378 http://dx.doi.org/10.1038/s41593-019-0422-3 |