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Stimulation of β‐adrenoceptors up‐regulates cardiac expression of galectin‐3 and BIM through the Hippo signalling pathway

BACKGROUND AND PURPOSE: Expression of the pro‐fibrotic galectin‐3 and the pro‐apoptotic BIM is elevated in diseased heart or after β‐adrenoceptor stimulation, but the underlying mechanisms are unclear. This question was addressed in the present study. EXPERIMENTAL APPROACH: Wild‐type mice and mice w...

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Detalles Bibliográficos
Autores principales: Zhao, Wei‐Bo, Lu, Qun, Nguyen, My‐Nhan, Su, Yidan, Ziemann, Mark, Wang, Li‐Na, Kiriazis, Helen, Puthalakath, Hamsa, Sadoshima, Junichi, Hu, Hou‐Yuan, Du, Xiao‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592853/
https://www.ncbi.nlm.nih.gov/pubmed/30932177
http://dx.doi.org/10.1111/bph.14674