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Stimulation of β‐adrenoceptors up‐regulates cardiac expression of galectin‐3 and BIM through the Hippo signalling pathway
BACKGROUND AND PURPOSE: Expression of the pro‐fibrotic galectin‐3 and the pro‐apoptotic BIM is elevated in diseased heart or after β‐adrenoceptor stimulation, but the underlying mechanisms are unclear. This question was addressed in the present study. EXPERIMENTAL APPROACH: Wild‐type mice and mice w...
Autores principales: | Zhao, Wei‐Bo, Lu, Qun, Nguyen, My‐Nhan, Su, Yidan, Ziemann, Mark, Wang, Li‐Na, Kiriazis, Helen, Puthalakath, Hamsa, Sadoshima, Junichi, Hu, Hou‐Yuan, Du, Xiao‐Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592853/ https://www.ncbi.nlm.nih.gov/pubmed/30932177 http://dx.doi.org/10.1111/bph.14674 |
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