Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture

Human induced pluripotent stem cells (hiPSCs) represent an almost limitless source of cells for disease modelling and drug screening applications. Here we established an efficient and robust 3D platform for cardiomyocyte (CMs) production from hiPSCs, solely through small-molecule-based temporal modu...

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Detalles Bibliográficos
Autores principales: Branco, Mariana A., Cotovio, João P., Rodrigues, Carlos A. V., Vaz, Sandra H., Fernandes, Tiago G., Moreira, Leonilde M., Cabral, Joaquim M. S., Diogo, Maria Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592905/
https://www.ncbi.nlm.nih.gov/pubmed/31239450
http://dx.doi.org/10.1038/s41598-019-45047-9

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