Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Neutralizing antibodies (nAbs) are a critical component for protection against dengue virus (DENV) infection, but little is known about the immune mechanisms governing their induction and whether such mechanisms can be harnessed for vaccine development. In this study, we profiled the early immune re...

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Detalles Bibliográficos
Autores principales: Bidet, Katell, Ho, Victor, Chu, Collins Wenhan, Naim, Ahmad Nazri Mohamed, Thazin, Khaing, Chan, Kuan Rong, Low, Jenny G. H., Choy, Milly M., Wong, Lan Hiong, Florez de Sessions, Paola, Lee, Yie Hou, Hibberd, Martin L., Ooi, Eng Eong, Fink, Katja, Chen, Jianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592935/
https://www.ncbi.nlm.nih.gov/pubmed/31285858
http://dx.doi.org/10.1038/s41541-019-0119-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592935/
https://www.ncbi.nlm.nih.gov/pubmed/31285858
http://dx.doi.org/10.1038/s41541-019-0119-3

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