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Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity
Neutralizing antibodies (nAbs) are a critical component for protection against dengue virus (DENV) infection, but little is known about the immune mechanisms governing their induction and whether such mechanisms can be harnessed for vaccine development. In this study, we profiled the early immune re...
Autores principales: | Bidet, Katell, Ho, Victor, Chu, Collins Wenhan, Naim, Ahmad Nazri Mohamed, Thazin, Khaing, Chan, Kuan Rong, Low, Jenny G. H., Choy, Milly M., Wong, Lan Hiong, Florez de Sessions, Paola, Lee, Yie Hou, Hibberd, Martin L., Ooi, Eng Eong, Fink, Katja, Chen, Jianzhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592935/ https://www.ncbi.nlm.nih.gov/pubmed/31285858 http://dx.doi.org/10.1038/s41541-019-0119-3 |
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