Early alterations in a mouse model of Rett syndrome: the GABA developmental shift is abolished at birth

Genetic mutations of the Methyl-CpG-binding protein-2 (MECP2) gene underlie Rett syndrome (RTT). Developmental processes are often considered to be irrelevant in RTT pathogenesis but neuronal activity at birth has not been recorded. We report that the GABA developmental shift at birth is abolished i...

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Detalles Bibliográficos
Autores principales: Lozovaya, N., Nardou, R., Tyzio, R., Chiesa, M., Pons-Bennaceur, A., Eftekhari, S., Bui, T.-T., Billon-Grand, M., Rasero, J., Bonifazi, P., Guimond, D., Gaiarsa, J.-L., Ferrari, D. C., Ben-Ari, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592949/
https://www.ncbi.nlm.nih.gov/pubmed/31239460
http://dx.doi.org/10.1038/s41598-019-45635-9

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