Parkin Impairs Antiviral Immunity by Suppressing the Mitochondrial Reactive Oxygen Species-Nlrp3 Axis and Antiviral Inflammation

Although mitochondria are known to be involved in host defense against viral infection, the physiological role of mitophagy, a crucial mechanism for maintaining mitochondrial homeostasis, in antiviral immunity remains poorly defined. Here, we show that Parkin, a central player in mitophagy, has a vi...

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Detalles Bibliográficos
Autores principales: Li, Jian, Ma, Chunmei, Long, Fei, Yang, Dongxue, Liu, Xue, Hu, Yingchao, Wu, Chunyan, Wang, Bingwei, Wang, Min, Chen, Yunzi, Liu, Genyan, Moynagh, Paul N., Zhou, Jiawei, Peng, Tao, Yang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593176/
https://www.ncbi.nlm.nih.gov/pubmed/31229895
http://dx.doi.org/10.1016/j.isci.2019.06.008

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