Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

Genomic profiling of circulating tumor DNA derived from cell-free DNA (cfDNA) in blood can provide a noninvasive method for detecting genomic biomarkers to guide clinical decision making for cancer patients. We developed a hybrid capture–based next-generation sequencing assay for genomic profiling o...

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Detalles Bibliográficos
Autores principales: Clark, Travis A., Chung, Jon H., Kennedy, Mark, Hughes, Jason D., Chennagiri, Niru, Lieber, Daniel S., Fendler, Bernard, Young, Lauren, Zhao, Mandy, Coyne, Michael, Breese, Virginia, Young, Geneva, Donahue, Amy, Pavlick, Dean, Tsiros, Alyssa, Brennan, Timothy, Zhong, Shan, Mughal, Tariq, Bailey, Mark, He, Jie, Roels, Steven, Frampton, Garrett M., Spoerke, Jill M., Gendreau, Steven, Lackner, Mark, Schleifman, Erica, Peters, Eric, Ross, Jeffrey S., Ali, Siraj M., Miller, Vincent A., Gregg, Jeffrey P., Stephens, Philip J., Welsh, Allison, Otto, Geoff A., Lipson, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593250/
https://www.ncbi.nlm.nih.gov/pubmed/29936259
http://dx.doi.org/10.1016/j.jmoldx.2018.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593250/
https://www.ncbi.nlm.nih.gov/pubmed/29936259
http://dx.doi.org/10.1016/j.jmoldx.2018.05.004

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