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Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats

Endocrine disruptors (EDs) are compounds that interfere with the balance of the endocrine system by mimicking or antagonising the effects of endogenous hormones, by altering the synthesis and metabolism of natural hormones, or by modifying hormone receptor levels. The synthetic estrogen 17α-ethinyle...

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Detalles Bibliográficos
Autores principales: Stiborová, Marie, Dračínská, Helena, Bořek-Dohalská, Lucie, Klusoňová, Zuzana, Holecová, Jana, Martínková, Markéta, Schmeiser, Heinz H., Arlt, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593260/
https://www.ncbi.nlm.nih.gov/pubmed/29649501
http://dx.doi.org/10.1016/j.tox.2018.04.001

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