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Molecular Simulations Reveal the Role of Antibody Fine Specificity and Viral Maturation State on Antibody-Dependent Enhancement of Infection in Dengue Virus

Recent clinical studies have revealed that severe symptoms of dengue fever are associated with low pre-existing antibody levels. These findings provide direct clinical evidence for the theory of antibody-dependent enhancement of infection (ADE), which postulates that sub-neutralizing levels of antib...

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Detalles Bibliográficos
Autores principales:	Ripoll, Daniel R., Wallqvist, Anders, Chaudhury, Sidhartha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593287/ https://www.ncbi.nlm.nih.gov/pubmed/31275864 http://dx.doi.org/10.3389/fcimb.2019.00200

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