Cargando…

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

Multiple myeloma is a fatal plasma cell malignancy that is reliant on the bone marrow microenvironment. The bone marrow is comprised of numerous cells of mesenchymal and hemopoietic origin. Of these, macrophages have been implicated to play a role in myeloma disease progression, angiogenesis, and dr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Opperman, Khatora S., Vandyke, Kate, Clark, Kimberley C., Coulter, Elizabeth A., Hewett, Duncan R., Mrozik, Krzysztof M., Schwarz, Nisha, Evdokiou, Andreas, Croucher, Peter I, Psaltis, Peter J, Noll, Jacqueline E, Zannettino, Andrew CW
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593350/ https://www.ncbi.nlm.nih.gov/pubmed/31247457 http://dx.doi.org/10.1016/j.neo.2019.05.006

Ejemplares similares

GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice
por: Friend, Natasha, et al.
Publicado: (2020)

LCRF‐0006, a small molecule mimetic of the N‐cadherin antagonist peptide ADH‐1, synergistically increases multiple myeloma response to bortezomib
por: Mrozik, Krzysztof M., et al.
Publicado: (2020)

Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo
por: Clark, Kimberley C., et al.
Publicado: (2020)

Expression of the chemokine receptor CCR1 promotes the dissemination of multiple myeloma plasma cells in vivo
por: Zeissig, Mara N., et al.
Publicado: (2020)

Characterization of the role of Samsn1 loss in multiple myeloma development
por: Friend, Natasha L., et al.
Publicado: (2020)

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma
por: Noll, Jacqueline E., et al.
Publicado: (2015)

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment
por: Hewett, Duncan R., et al.
Publicado: (2017)

Macrophage depletion by clodronate liposome attenuates muscle injury and inflammation following exhaustive exercise
por: Kawanishi, Noriaki, et al.
Publicado: (2015)

Use of Clodronate Liposomes to Deplete Phagocytic Immune Cells in Drosophila melanogaster and Aedes aegypti
por: Ramesh Kumar, Jyothsna, et al.
Publicado: (2021)

Depletion of macrophages with clodronate liposomes partially attenuates renal fibrosis on AKI–CKD transition
por: Hu, Zhizhi, et al.
Publicado: (2023)

Indirect osteoblast differentiation by liposomal clodronate
por: Okada, Emi, et al.
Publicado: (2017)

SAMSN1 Is a Tumor Suppressor Gene in Multiple Myeloma()()
por: Noll, Jacqueline E., et al.
Publicado: (2014)

Isolation of High Purity Mouse Mesenchymal Stem Cells through Depleting Macrophages Using Liposomal Clodronate
por: Song, Ju Han, et al.
Publicado: (2022)

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach
por: Zeisberger, S M, et al.
Publicado: (2006)

Clodronate Liposome-Mediated Phagocytic Hemocyte Depletion Affects the Regeneration of the Cephalic Tentacle of the Invasive Snail, Pomacea canaliculata
por: Bergamini, Giulia, et al.
Publicado: (2023)

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes
por: Culemann, Stephan, et al.
Publicado: (2023)

Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures
por: Kumamaru, Hiromi, et al.
Publicado: (2012)

The stunning clodronate
por: Mass, Elvira
Publicado: (2023)

N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer
por: Mrozik, Krzysztof Marek, et al.
Publicado: (2018)

Effect of clodronate-liposome injections on Plasmodium falciparum infection in neo-tropical primates Saimiri sciureus
por: Cunha, Janaiara A, et al.
Publicado: (2014)

Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes
por: Cunha, Janaiara A., et al.
Publicado: (2017)

Clodronate liposomes may biases MSC differentiation toward adipogenesis through activation of NLRP3
por: Ding, Shuang, et al.
Publicado: (2023)

Macrophage Depletion via Clodronate Pretreatment Reduces Transgene Expression from AAV Vectors In Vivo
por: Yu, Darrick L., et al.
Publicado: (2021)

Treatment of malignant hypercalcaemia with clodronate.
por: Percival, R. C., et al.
Publicado: (1985)

Tumour Dissemination in Multiple Myeloma Disease Progression and Relapse: A Potential Therapeutic Target in High-Risk Myeloma
por: Zeissig, Mara N., et al.
Publicado: (2020)

Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice
por: Feng, Bin, et al.
Publicado: (2011)

The Macrophage-depleting Agent Clodronate Promotes Durable Hematopoietic Chimerism and Donor-specific Skin Allograft Tolerance in Mice
por: Li, Zhanzhuo, et al.
Publicado: (2016)

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress
por: Wallington-Beddoe, Craig T., et al.
Publicado: (2017)

Meta-analysis of clodronate and breast cancer survival
por: Ha, T C, et al.
Publicado: (2007)

Clodronate as a Therapeutic Strategy against Osteoarthritis
por: Valenti, Maria Teresa, et al.
Publicado: (2017)

The Rationale for the Intra-Articular Administration of Clodronate in Osteoarthritis
por: Moretti, Antimo, et al.
Publicado: (2021)

Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine storm in COVID-19
por: Ravichandran, Sowbarnika, et al.
Publicado: (2022)

The tyrosine kinase inhibitor dasatinib (SPRYCEL) inhibits chondrocyte activity and proliferation
por: Vandyke, K, et al.
Publicado: (2011)

Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment
por: Kim, Munkyung, et al.
Publicado: (2015)

Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate
por: Taoka, Kazuki, et al.
Publicado: (2018)

In vivo tracking of transplanted macrophages with near infrared fluorescent dye reveals temporal distribution and specific homing in the liver that can be perturbed by clodronate liposomes
por: Nishiwaki, Satoshi, et al.
Publicado: (2020)

Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats
por: Vichaya, Elisabeth G., et al.
Publicado: (2020)

Plant-derived soybean peroxidase stimulates osteoblast collagen biosynthesis, matrix mineralization, and accelerates bone regeneration in a sheep model
por: Barker, Alexandra J., et al.
Publicado: (2021)

Using genomics to better define high-risk MGUS/SMM patients
por: Dutta, Ankit K., et al.
Publicado: (2018)

Is there a dose response relationship for clodronate in the treatment of tumour induced hypercalcaemia?
por: Shah, S, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_apu5d559vnag6676t6cfpdu5fo