HIV Silencing and Inducibility Are Heterogeneous and Are Affected by Factors Intrinsic to the Virus

Transcriptionally silent HIV proviruses form the major obstacle to eradicating HIV. Many studies of HIV latency have focused on the cellular mechanisms that maintain silencing of proviral DNA. Here we show that viral sequence variation affecting replicative ability leads to variable rates of silenci...

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Detalles Bibliográficos
Autores principales: Norton, Nicholas J., Mok, Hoi Ping, Sharif, Fatima, Hirst, Jack C., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593397/
https://www.ncbi.nlm.nih.gov/pubmed/31239371
http://dx.doi.org/10.1128/mBio.00188-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593397/
https://www.ncbi.nlm.nih.gov/pubmed/31239371
http://dx.doi.org/10.1128/mBio.00188-19

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