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HIV Silencing and Inducibility Are Heterogeneous and Are Affected by Factors Intrinsic to the Virus
Transcriptionally silent HIV proviruses form the major obstacle to eradicating HIV. Many studies of HIV latency have focused on the cellular mechanisms that maintain silencing of proviral DNA. Here we show that viral sequence variation affecting replicative ability leads to variable rates of silenci...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593397/ https://www.ncbi.nlm.nih.gov/pubmed/31239371 http://dx.doi.org/10.1128/mBio.00188-19 |