Cargando…
Helix-A peptide prevents gp120-mediated neuronal loss
AIM: The human-immunodeficiency virus (HIV) envelope protein gp120 promotes synaptic damage similar to that observed in people living with HIV who have neurocognitive disorders. The neurotoxic effect of gp120 appears to occur through the α-helix motif that binds to neuronal microtubules (MTs). In th...
Autores principales: | Avdoshina, Valeria, Taraballi, Francesca, Tasciotti, Ennio, Üren, Aykut, Mocchetti, Italo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593494/ https://www.ncbi.nlm.nih.gov/pubmed/31238994 http://dx.doi.org/10.1186/s13041-019-0482-z |
Ejemplares similares
-
Recent Advances in the Molecular and Cellular Mechanisms of gp120-Mediated Neurotoxicity
por: Avdoshina, Valeria, et al.
Publicado: (2022) -
Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor
por: Speidell, Andrew, et al.
Publicado: (2019) -
Histone deacetylase 6 inhibition rescues axonal transport impairments and prevents the neurotoxicity of HIV-1 envelope protein gp120
por: Wenzel, Erin D., et al.
Publicado: (2019) -
Human immunodeficiency virus Tat impairs mitochondrial fission in neurons
por: Rozzi, Summer J., et al.
Publicado: (2018) -
Exogenous expression of an allatotropin-related peptide receptor increased the membrane excitability in Aplysia neurons
por: Zhang, Guo, et al.
Publicado: (2022)