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Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy

BACKGROUND: Multiple cartilaginous exostoses are a rare, benign, proliferative condition of cartilage and bone. They can be asymptomatic, or they may cause pain, lameness, paresis and even paralysis, depending on their location and size. In cases of spinal cord or nerve root compression, surgery is...

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Autores principales: Czerwik, Adriana, Olszewska, Agnieszka, Starzomska, Barbara, Korta, Rafał, Henrich, Manfred, Wrzosek, Marcin, Schmidt, Martin Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593590/
https://www.ncbi.nlm.nih.gov/pubmed/31238951
http://dx.doi.org/10.1186/s13028-019-0467-z
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author Czerwik, Adriana
Olszewska, Agnieszka
Starzomska, Barbara
Korta, Rafał
Henrich, Manfred
Wrzosek, Marcin
Schmidt, Martin Jürgen
author_facet Czerwik, Adriana
Olszewska, Agnieszka
Starzomska, Barbara
Korta, Rafał
Henrich, Manfred
Wrzosek, Marcin
Schmidt, Martin Jürgen
author_sort Czerwik, Adriana
collection PubMed
description BACKGROUND: Multiple cartilaginous exostoses are a rare, benign, proliferative condition of cartilage and bone. They can be asymptomatic, or they may cause pain, lameness, paresis and even paralysis, depending on their location and size. In cases of spinal cord or nerve root compression, surgery is the treatment of choice. Therefore, an advanced imaging diagnostic work-up is indicated. Due to the unclear pathophysiology and progression of this condition, it is difficult to predict its prognosis. CASE PRESENTATION: A 9-month-old female Swiss Mountain dog was presented with a history of gait abnormalities, kyphosis and hypersensitivity consistent with a thoracolumbar myelopathy. Multiple calcified masses, most prominent at the Th7–Th9 level and the L2–L3 level, were observed. Magnetic resonance imaging of the thoracolumbar vertebral column revealed severe dorsal spinal cord compressions near the dorsal arch of the Th7–Th9 and L2–L3 vertebrae. Two of these masses were removed surgically. The successful removal of both masses was confirmed by postoperative computed tomography. The histopathological examination of the resected tissue revealed multiple cartilaginous exostoses. The first neurological and magnetic resonance follow up examination carried out 6 months postoperatively showed improvement of the clinical status. At that time, no mass regrowth was observed. The last follow up neurological examination carried out 15 months postoperatively showed gait improvement and resolution of pain. CONCLUSION: This is the first case report of multiple cartilaginous exostoses with a complete pre- and postoperative evaluation and a 15 month follow-up.
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spelling pubmed-65935902019-07-09 Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy Czerwik, Adriana Olszewska, Agnieszka Starzomska, Barbara Korta, Rafał Henrich, Manfred Wrzosek, Marcin Schmidt, Martin Jürgen Acta Vet Scand Case Report BACKGROUND: Multiple cartilaginous exostoses are a rare, benign, proliferative condition of cartilage and bone. They can be asymptomatic, or they may cause pain, lameness, paresis and even paralysis, depending on their location and size. In cases of spinal cord or nerve root compression, surgery is the treatment of choice. Therefore, an advanced imaging diagnostic work-up is indicated. Due to the unclear pathophysiology and progression of this condition, it is difficult to predict its prognosis. CASE PRESENTATION: A 9-month-old female Swiss Mountain dog was presented with a history of gait abnormalities, kyphosis and hypersensitivity consistent with a thoracolumbar myelopathy. Multiple calcified masses, most prominent at the Th7–Th9 level and the L2–L3 level, were observed. Magnetic resonance imaging of the thoracolumbar vertebral column revealed severe dorsal spinal cord compressions near the dorsal arch of the Th7–Th9 and L2–L3 vertebrae. Two of these masses were removed surgically. The successful removal of both masses was confirmed by postoperative computed tomography. The histopathological examination of the resected tissue revealed multiple cartilaginous exostoses. The first neurological and magnetic resonance follow up examination carried out 6 months postoperatively showed improvement of the clinical status. At that time, no mass regrowth was observed. The last follow up neurological examination carried out 15 months postoperatively showed gait improvement and resolution of pain. CONCLUSION: This is the first case report of multiple cartilaginous exostoses with a complete pre- and postoperative evaluation and a 15 month follow-up. BioMed Central 2019-06-25 /pmc/articles/PMC6593590/ /pubmed/31238951 http://dx.doi.org/10.1186/s13028-019-0467-z Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Czerwik, Adriana
Olszewska, Agnieszka
Starzomska, Barbara
Korta, Rafał
Henrich, Manfred
Wrzosek, Marcin
Schmidt, Martin Jürgen
Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title_full Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title_fullStr Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title_full_unstemmed Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title_short Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy
title_sort multiple cartilaginous exostoses in a swiss mountain dog causing thoracolumbar compressive myelopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593590/
https://www.ncbi.nlm.nih.gov/pubmed/31238951
http://dx.doi.org/10.1186/s13028-019-0467-z
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