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Hypotonicity differentially affects inflammatory marker production by nucleus pulposus tissue in simulated disc degeneration versus herniation

Inflammatory cytokines play an important role in intervertebral disc degeneration. Although largely produced by immune cells, nucleus pulposus (NP) cells can also secrete them under various conditions, for example, under free swelling. Thus, tissue hypotonicity may be an inflammatory trigger for NP...

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Detalles Bibliográficos
Autores principales: Mouser, Vivian H. M., Arkesteijn, Irene T. M., van Dijk, Bart G. M., Wuertz‐Kozak, Karin, Ito, Keita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593810/
https://www.ncbi.nlm.nih.gov/pubmed/30835843
http://dx.doi.org/10.1002/jor.24268

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