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Transgenic increase in the β‐endorphin concentration in cerebrospinal fluid alleviates morphine‐primed relapse behavior through the μ opioid receptor in rats

BACKGROUND: Opioid‐primed relapse is a global burden. Although current strategies have improved, optimal therapy is urgently needed. METHODS: A recombinant adenovirus (Ad‐NEP) expressing β‐endorphin (β‐EP) was designed and injected intracerebroventricularly (icv) into the right lateral ventricle in...

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Detalles Bibliográficos
Autores principales:	He, Yan, Lu, Yugang, Shen, Yang, Wu, Feixiang, Xu, Xuewu, Kong, Erliang, Huang, Zhangxiang, Sun, Yuming, Yu, Weifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593851/ https://www.ncbi.nlm.nih.gov/pubmed/30701563 http://dx.doi.org/10.1002/jmv.25415

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