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APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology

Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer’s disease (AD). Numerous studies have provided insights into the pathologic mechanisms. However, a comprehensive understanding of the impact of APOE genotype on microflora speciation and metabolism is compl...

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Detalles Bibliográficos
Autores principales:	Tran, Tam T. T., Corsini, Simone, Kellingray, Lee, Hegarty, Claire, Le Gall, Gwénaëlle, Narbad, Arjan, Müller, Michael, Tejera, Noemi, O’Toole, Paul W., Minihane, Anne-Marie, Vauzour, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593891/ https://www.ncbi.nlm.nih.gov/pubmed/30958695 http://dx.doi.org/10.1096/fj.201900071R

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