Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms such as certain B cell lymphomas and multiple myelo...

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Detalles Bibliográficos
Autores principales: McBride, Kevin M., Kil, Hyunsuk, Mu, Yunxiang, Plummer, Joshua B., Lee, Jaeho, Zelazowski, Maciej J., Sebastian, Manu, Abba, Martin C., Aldaz, C. Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593956/
https://www.ncbi.nlm.nih.gov/pubmed/31275852
http://dx.doi.org/10.3389/fonc.2019.00517

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