Regorefenib induces extrinsic/intrinsic apoptosis and inhibits MAPK/NF‐κB‐modulated tumor progression in bladder cancer in vitro and in vivo

The aim of the present study is to investigate anticancer effect and mechanism of regorafenib in bladder cancer in vitro and in vivo. Human bladder cancer TSGH 8301 cells were treated with regorafenib, NF‐κB, AKT, or mitogen‐activated protein kinase (MAPK) inhibitors for different time. The changes...

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Detalles Bibliográficos
Autores principales: Chiang, Chih‐Hung, Chung, Jing‐Gung, Hsu, Fei‐Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594039/
https://www.ncbi.nlm.nih.gov/pubmed/30801954
http://dx.doi.org/10.1002/tox.22734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594039/
https://www.ncbi.nlm.nih.gov/pubmed/30801954
http://dx.doi.org/10.1002/tox.22734

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