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Genetics of Female Infertility: Molecular Study of Newborn Ovary Homeobox Gene in Poor Ovarian Responders

BACKGROUND: Newborn ovary homeobox (NOBOX) gene plays a critical role in the transcriptional regulation of oocyte-specific genes. Previous studies have demonstrated a pathogenic effect of NOBOX variants on premature ovarian insufficiency (POI) patients. Poor ovarian response (POR) is a risk factor f...

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Detalles Bibliográficos
Autores principales: Batiha, Osamah, Alahmad, Nour Alhoda, Sindiani, Amer, Bodoor, Khaldon, Shaaban, Sherin, Al-Smadi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594122/
https://www.ncbi.nlm.nih.gov/pubmed/31293321
http://dx.doi.org/10.4103/jhrs.JHRS_112_18