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Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

The observation that amyloid radiotracers developed for Alzheimer's disease bind to cerebral white matter paved the road to nuclear imaging of myelin in multiple sclerosis. The lysolecithin (lysophosphatidylcholine (LPC)) rat model of demyelination proved useful in evaluating and comparing cand...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Hugon, Gaëlle, Bouillot, Caroline, Bolbos, Radu, Langlois, Jean-Baptiste, Billard, Thierry, Bonnefoi, Frédéric, Li, Biao, Zimmer, Luc, Chauveau, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594279/
https://www.ncbi.nlm.nih.gov/pubmed/31281236
http://dx.doi.org/10.1155/2019/9294586