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Recombinant α-Klotho Protein Alleviated Acute Cardiorenal Injury in a Mouse Model of Lipopolysaccharide-Induced Septic Cardiorenal Syndrome Type 5

BACKGROUND AND AIMS: Klotho is an aging-suppressor gene mainly expressed in the renal tubules. The klotho gene encodes the α-klotho protein, which has many functions. Previous studies have found that α-klotho protein has a cardiorenal protective function. α-Klotho deficiency renders the kidney more...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Niu, Yangyang, Zhang, Xiaoqin, Zhang, Yingying, Yu, Ying, Huang, Jieli, Li, Jiangtao, Yu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594328/
https://www.ncbi.nlm.nih.gov/pubmed/31309036
http://dx.doi.org/10.1155/2019/5853426

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