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Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro
Localized electric fields have become, in recent years, a source of inspiration to researchers and laboratories thanks to a huge amount of applications derived from it, including positioning of microparticles as building blocks for electrical, optical, and magnetic devices. The possibility of produc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594357/ https://www.ncbi.nlm.nih.gov/pubmed/31275921 http://dx.doi.org/10.3389/fchem.2019.00429 |
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author | Rega, Romina Gennari, Oriella Mecozzi, Laura Pagliarulo, Vito Mugnano, Martina Oleandro, Emilia Nazzaro, Filomena Ferraro, Pietro Grilli, Simonetta |
author_facet | Rega, Romina Gennari, Oriella Mecozzi, Laura Pagliarulo, Vito Mugnano, Martina Oleandro, Emilia Nazzaro, Filomena Ferraro, Pietro Grilli, Simonetta |
author_sort | Rega, Romina |
collection | PubMed |
description | Localized electric fields have become, in recent years, a source of inspiration to researchers and laboratories thanks to a huge amount of applications derived from it, including positioning of microparticles as building blocks for electrical, optical, and magnetic devices. The possibility of producing polymeric materials with surface charge thus opens new perspectives for applications where process simplicity and cost-effectiveness of flexible electronics are of fundamental importance. In particular, the influence of surface charges is widely studied and is a critical issue especially when new materials and functional technologies are introduced. Here, we report a voltage-free pyro-electrification (PE) process able to induce a permanent dipole orientation into polymer sheets under both mono- and bipolar distribution. The technique makes use of the pyroelectric effect for generating electric potentials on the order of kilovolts by an easy-to-accomplish thermal treatment of ferroelectric lithium niobate (LN) crystals. The PE allows us to avoid the expensive and time-consuming fabrication of high-power electrical circuits, as occurs in traditional generator-based techniques. Since the technique is fully compatible with spin-coating-based procedures, the pyro-electrified polymer sheets are easily peeled off the surface of the LN crystal after PE completion, thus providing highly stable and freestanding charged sheets. We show the reliability of the technique for different polymers and for different applications ranging from live cell patterning to biofilm formation tests for bacteria linked to food-processing environments. |
format | Online Article Text |
id | pubmed-6594357 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-65943572019-07-03 Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro Rega, Romina Gennari, Oriella Mecozzi, Laura Pagliarulo, Vito Mugnano, Martina Oleandro, Emilia Nazzaro, Filomena Ferraro, Pietro Grilli, Simonetta Front Chem Chemistry Localized electric fields have become, in recent years, a source of inspiration to researchers and laboratories thanks to a huge amount of applications derived from it, including positioning of microparticles as building blocks for electrical, optical, and magnetic devices. The possibility of producing polymeric materials with surface charge thus opens new perspectives for applications where process simplicity and cost-effectiveness of flexible electronics are of fundamental importance. In particular, the influence of surface charges is widely studied and is a critical issue especially when new materials and functional technologies are introduced. Here, we report a voltage-free pyro-electrification (PE) process able to induce a permanent dipole orientation into polymer sheets under both mono- and bipolar distribution. The technique makes use of the pyroelectric effect for generating electric potentials on the order of kilovolts by an easy-to-accomplish thermal treatment of ferroelectric lithium niobate (LN) crystals. The PE allows us to avoid the expensive and time-consuming fabrication of high-power electrical circuits, as occurs in traditional generator-based techniques. Since the technique is fully compatible with spin-coating-based procedures, the pyro-electrified polymer sheets are easily peeled off the surface of the LN crystal after PE completion, thus providing highly stable and freestanding charged sheets. We show the reliability of the technique for different polymers and for different applications ranging from live cell patterning to biofilm formation tests for bacteria linked to food-processing environments. Frontiers Media S.A. 2019-06-19 /pmc/articles/PMC6594357/ /pubmed/31275921 http://dx.doi.org/10.3389/fchem.2019.00429 Text en Copyright © 2019 Rega, Gennari, Mecozzi, Pagliarulo, Mugnano, Oleandro, Nazzaro, Ferraro and Grilli. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Rega, Romina Gennari, Oriella Mecozzi, Laura Pagliarulo, Vito Mugnano, Martina Oleandro, Emilia Nazzaro, Filomena Ferraro, Pietro Grilli, Simonetta Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title | Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title_full | Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title_fullStr | Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title_full_unstemmed | Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title_short | Pyro-Electrification of Freestanding Polymer Sheets: A New Tool for Cation-Free Manipulation of Cell Adhesion in vitro |
title_sort | pyro-electrification of freestanding polymer sheets: a new tool for cation-free manipulation of cell adhesion in vitro |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594357/ https://www.ncbi.nlm.nih.gov/pubmed/31275921 http://dx.doi.org/10.3389/fchem.2019.00429 |
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