Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses

Plant molecular pharming has emerged as a reliable platform for recombinant protein expression providing a safe and low-cost alternative to bacterial and mammalian cells-based systems. Simultaneously, plant viruses have evolved from pathogens to molecular tools for recombinant protein expression, ch...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ahmad, Odon, Valerie, Kormelink, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594412/
https://www.ncbi.nlm.nih.gov/pubmed/31275344
http://dx.doi.org/10.3389/fpls.2019.00803
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author Ibrahim, Ahmad
Odon, Valerie
Kormelink, Richard
author_facet Ibrahim, Ahmad
Odon, Valerie
Kormelink, Richard
author_sort Ibrahim, Ahmad
collection PubMed
description Plant molecular pharming has emerged as a reliable platform for recombinant protein expression providing a safe and low-cost alternative to bacterial and mammalian cells-based systems. Simultaneously, plant viruses have evolved from pathogens to molecular tools for recombinant protein expression, chimaeric viral vaccine production, and lately, as nanoagents for drug delivery. This review summarizes the genesis of viral vectors and agroinfection, the development of non-enveloped viruses for various biotechnological applications, and the on-going research on enveloped plant viruses.
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spelling pubmed-65944122019-07-03 Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses Ibrahim, Ahmad Odon, Valerie Kormelink, Richard Front Plant Sci Plant Science Plant molecular pharming has emerged as a reliable platform for recombinant protein expression providing a safe and low-cost alternative to bacterial and mammalian cells-based systems. Simultaneously, plant viruses have evolved from pathogens to molecular tools for recombinant protein expression, chimaeric viral vaccine production, and lately, as nanoagents for drug delivery. This review summarizes the genesis of viral vectors and agroinfection, the development of non-enveloped viruses for various biotechnological applications, and the on-going research on enveloped plant viruses. Frontiers Media S.A. 2019-06-19 /pmc/articles/PMC6594412/ /pubmed/31275344 http://dx.doi.org/10.3389/fpls.2019.00803 Text en Copyright © 2019 Ibrahim, Odon and Kormelink. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Ibrahim, Ahmad
Odon, Valerie
Kormelink, Richard
Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title_full Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title_fullStr Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title_full_unstemmed Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title_short Plant Viruses in Plant Molecular Pharming: Toward the Use of Enveloped Viruses
title_sort plant viruses in plant molecular pharming: toward the use of enveloped viruses
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594412/
https://www.ncbi.nlm.nih.gov/pubmed/31275344
http://dx.doi.org/10.3389/fpls.2019.00803
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