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Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells
Activation of the epidermal growth factor (EGF) receptor (EGFR) at the cell surface initiates signaling through the RAS-RAF-MAPK/ERK1/2 pathway and receptor endocytosis. Whether this signaling continues from endosomes remains unclear, because RAS is predominantly located on the plasma membrane, and...
Autores principales: | Surve, Sachin V., Myers, Paul J., Clayton, Samantha A., Watkins, Simon C., Lazzara, Matthew J., Sorkin, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594441/ https://www.ncbi.nlm.nih.gov/pubmed/30586319 http://dx.doi.org/10.1091/mbc.E18-08-0512 |
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