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Kinetic analysis of transcellular passage of the cobalamin–transcobalamin complex in Caco-2 monolayers
We suggest a novel kinetic approach to quantifying receptor–ligand interactions via the cellular transport and/or accumulation of the ligand. The system of cobalamin (Cbl, vitamin B12) transport was used as a model, because Cbl is an obligatory cofactor, taken up by animal cells with the help of a t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594447/ https://www.ncbi.nlm.nih.gov/pubmed/30565973 http://dx.doi.org/10.1091/mbc.E18-09-0571 |