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GAD mRNA in Orbital Prefrontal Cortex and Anterior Cingulate Cortex in Alcoholics Compared with Nonpsychiatric Controls: A Negative Postmortem Study
Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We sought to determine the amount of GAD(65/67) mRNA in anterior...
Autores principales: | Underwood, Mark D., Bakalian, Mihran J., Dwork, Andrew J., Min, Eli, Mann, J. John, Arango, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594560/ https://www.ncbi.nlm.nih.gov/pubmed/31245628 http://dx.doi.org/10.20900/jpbs.20190007 |
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