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Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes
The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-like (B-13/H) cells in response to glucocorticoid. Since this response is dependent on an induction of serine/threonine protein kinase 1 (SGK1), this may suggest that a general pivotal role for SGK1 in hepat...
Autores principales: | Alsaeedi, Fouzeyyah, Wilson, Rachel, Candlish, Charlotte, Ibrahim, Ibrahim, Leitch, Alistair C., Abdelghany, Tarek M., Wilson, Colin, Armstrong, Lyle, Wright, Matthew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594595/ https://www.ncbi.nlm.nih.gov/pubmed/31242206 http://dx.doi.org/10.1371/journal.pone.0218135 |
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