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Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures

An emerging cellular immunotherapy for cancer is based on the cytolytic activity of natural killer (NK) cells against a wide range of tumors. Although in vitro activation, or “priming,” of NK cells by exposure to pro-inflammatory cytokines, such as interleukin (IL)-2, has been extensively studied, t...

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Detalles Bibliográficos
Autores principales:	Sabry, May, Zubiak, Agnieszka, Hood, Simon P., Simmonds, Poppy, Arellano-Ballestero, Helena, Cournoyer, Eily, Mashar, Meghavi, Pockley, A. Graham, Lowdell, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594622/ https://www.ncbi.nlm.nih.gov/pubmed/31242243 http://dx.doi.org/10.1371/journal.pone.0218674

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