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Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses
Mitochondrial antiviral signaling protein (MAVS) is a critical innate immune signaling protein that directs the actions of the RIG-I-like receptor (RLR) signaling pathway of RNA virus recognition and initiation of anti-viral immunity against West Nile virus (WNV). In the absence of MAVS, mice die mo...
Autores principales: | Roe, Kelsey, Giordano, Daniela, Young, Lucy B., Draves, Kevin E., Holder, Ursula, Suthar, Mehul S., Gale, Michael, Clark, Edward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594639/ https://www.ncbi.nlm.nih.gov/pubmed/31242236 http://dx.doi.org/10.1371/journal.pone.0218928 |
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