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Nutrient availability shapes methionine metabolism in p16/MTAP-deleted cells

Codeletions of gene loci containing tumor suppressors and neighboring metabolic enzymes present an attractive synthetic dependency in cancers. However, the impact that these genetic events have on metabolic processes, which are also dependent on nutrient availability and other environmental factors,...

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Detalles Bibliográficos
Autores principales:	Sanderson, Sydney M., Mikhael, Peter G., Ramesh, Vijyendra, Dai, Ziwei, Locasale, Jason W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594760/ https://www.ncbi.nlm.nih.gov/pubmed/31249865 http://dx.doi.org/10.1126/sciadv.aav7769

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