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Experimental evidence for the age dependence of tau protein spread in the brain

The incidence of Alzheimer’s disease (AD), which is characterized by progressive cognitive decline that correlates with the spread of tau protein aggregation in the cortical mantle, is strongly age-related. It could be that age predisposes the brain for tau misfolding and supports the propagation of...

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Detalles Bibliográficos
Autores principales: Wegmann, Susanne, Bennett, Rachel E., Delorme, Louis, Robbins, Ashley B., Hu, Miwei, McKenzie, Danny, Kirk, Molly J., Schiantarelli, Julia, Tunio, Nahel, Amaral, Ana C., Fan, Zhanyun, Nicholls, Samantha, Hudry, Eloise, Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594764/
https://www.ncbi.nlm.nih.gov/pubmed/31249873
http://dx.doi.org/10.1126/sciadv.aaw6404

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