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Experimental evidence for the age dependence of tau protein spread in the brain
The incidence of Alzheimer’s disease (AD), which is characterized by progressive cognitive decline that correlates with the spread of tau protein aggregation in the cortical mantle, is strongly age-related. It could be that age predisposes the brain for tau misfolding and supports the propagation of...
Autores principales: | Wegmann, Susanne, Bennett, Rachel E., Delorme, Louis, Robbins, Ashley B., Hu, Miwei, McKenzie, Danny, Kirk, Molly J., Schiantarelli, Julia, Tunio, Nahel, Amaral, Ana C., Fan, Zhanyun, Nicholls, Samantha, Hudry, Eloise, Hyman, Bradley T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594764/ https://www.ncbi.nlm.nih.gov/pubmed/31249873 http://dx.doi.org/10.1126/sciadv.aaw6404 |
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