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Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases
Collective cell migration occurs in many patho-physiological states, including wound healing and invasive cancer growth. The integrity of the expanding epithelial sheets depends on extracellular cues, including cell-cell and cell-matrix interactions. We show that the nano-scale topography of the ext...
Autores principales: | Park, JinSeok, Kim, Deok-Ho, Shah, Sagar R., Kim, Hong-Nam, Kshitiz, Kim, Peter, Quiñones-Hinojosa, Alfredo, Levchenko, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594963/ https://www.ncbi.nlm.nih.gov/pubmed/31243273 http://dx.doi.org/10.1038/s41467-019-10729-5 |
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