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Common and distinct transcriptional signatures of mammalian embryonic lethality

The Deciphering the Mechanisms of Developmental Disorders programme has analysed the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines in order to investigate the causes of embryonic lethality. Here we show that individual whole-embryo RNA-seq of 73 mouse mu...

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Detalles Bibliográficos
Autores principales:	Collins, John E., White, Richard J., Staudt, Nicole, Sealy, Ian M., Packham, Ian, Wali, Neha, Tudor, Catherine, Mazzeo, Cecilia, Green, Angela, Siragher, Emma, Ryder, Edward, White, Jacqueline K., Papatheodoru, Irene, Tang, Amy, Füllgrabe, Anja, Billis, Konstantinos, Geyer, Stefan H., Weninger, Wolfgang J., Galli, Antonella, Hemberger, Myriam, Stemple, Derek L., Robertson, Elizabeth, Smith, James C., Mohun, Timothy, Adams, David J., Busch-Nentwich, Elisabeth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594971/ https://www.ncbi.nlm.nih.gov/pubmed/31243271 http://dx.doi.org/10.1038/s41467-019-10642-x

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