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Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Many potentially therapeutic molecules have been identified for treating Duchenne muscular dystrophy. However, targeting those molecules only to sites of active pathology is an obstacle to their clinical use. Because dystrophic muscles become extensively inflamed, we tested whether expressing a ther...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594976/ https://www.ncbi.nlm.nih.gov/pubmed/31243277 http://dx.doi.org/10.1038/s41467-019-10614-1 |