Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry

Triclofos sodium (TCS) and chloral hydrate (CH) are widely used as sedatives for children, but no analytical method to simultaneously monitor concentrations of blood TCS, CH and their metabolites, trichloroacetic acid (TCA) and trichloroethanol (TCEOH), has been reported. The present study aimed to...

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Detalles Bibliográficos
Autores principales: Sato, Hirotaka, Ito, Yuki, Inoue, Miho, Nakahira, Yuki, Hashimoto, Satoru, Nakajima, Tamie, Kamijima, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594997/
https://www.ncbi.nlm.nih.gov/pubmed/31243319
http://dx.doi.org/10.1038/s41598-019-45790-z

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