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Myocardial death and dysfunction after ischemia-reperfusion injury require CaMKIIδ oxidation

Reactive oxygen species (ROS) contribute to myocardial death during ischemia-reperfusion (I/R) injury, but detailed knowledge of molecular pathways connecting ROS to cardiac injury is lacking. Activation of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKIIδ) is implicated in myocardial death...

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Detalles Bibliográficos
Autores principales: Wu, Yuejin, Wang, Qinchuan, Feng, Ning, Granger, Jonathan M., Anderson, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595001/
https://www.ncbi.nlm.nih.gov/pubmed/31243295
http://dx.doi.org/10.1038/s41598-019-45743-6

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