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Development of a CRISPR/Cas9-Based Tool for Gene Deletion in Issatchenkia orientalis
The nonconventional yeast Issatchenkia orientalis has emerged as a potential platform microorganism for production of organic acids due to its ability to grow robustly under highly acidic conditions. However, lack of efficient genetic tools remains a major bottleneck in metabolic engineering of this...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595149/ https://www.ncbi.nlm.nih.gov/pubmed/31243078 http://dx.doi.org/10.1128/mSphere.00345-19 |