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Susceptibility to Medium-Chain Fatty Acids Is Associated with Trisomy of Chromosome 7 in Candida albicans

Fatty acids have known antifungal effects and are used in over-the-counter topical treatments. Screening of a collection of gene knockouts in Candida albicans revealed that one strain, carrying a deletion of the transcription factor DAL81, is very susceptible to the medium-chain fatty acid undecanoi...

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Detalles Bibliográficos
Autores principales: Ma, Qinxi, Ola, Mihaela, Iracane, Elise, Butler, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595153/
https://www.ncbi.nlm.nih.gov/pubmed/31243082
http://dx.doi.org/10.1128/mSphere.00402-19