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Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera

BACKGROUND: Gait alterations are hallmarks for the diagnosis and follow-up of patients with Parkinson's disease (PD). In normal conditions, age could affect gait dynamics. Although it is known that objective assessment of gait is a valuable tool for diagnosis and follow-up of patients with PD,...

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Autores principales: Muñoz Ospina, Beatriz, Valderrama Chaparro, Jaime Andrés, Arango Paredes, Juan David, Castaño Pino, Yor Jaggy, Navarro, Andrés, Orozco, Jorge Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595395/
https://www.ncbi.nlm.nih.gov/pubmed/31312423
http://dx.doi.org/10.1155/2019/5050182
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author Muñoz Ospina, Beatriz
Valderrama Chaparro, Jaime Andrés
Arango Paredes, Juan David
Castaño Pino, Yor Jaggy
Navarro, Andrés
Orozco, Jorge Luis
author_facet Muñoz Ospina, Beatriz
Valderrama Chaparro, Jaime Andrés
Arango Paredes, Juan David
Castaño Pino, Yor Jaggy
Navarro, Andrés
Orozco, Jorge Luis
author_sort Muñoz Ospina, Beatriz
collection PubMed
description BACKGROUND: Gait alterations are hallmarks for the diagnosis and follow-up of patients with Parkinson's disease (PD). In normal conditions, age could affect gait dynamics. Although it is known that objective assessment of gait is a valuable tool for diagnosis and follow-up of patients with PD, only few studies evaluate the effect of aging on the gait pattern of patients with PD. OBJECTIVE: The purpose of this study was to assess differences in gait dynamics between PD patients and healthy subjects and to investigate the effects of aging on these differences using a low-cost RGB-D depth-sensing camera. METHODS: 30 PD patients and 30 age-matched controls were recruited. Descriptive analysis was used for clinical variables, and Spearman's rank correlation was used to correlate age and gait variables. The sample was distributed in age groups; then, Mann–Whitney U test was used for comparison of gait variables between groups. RESULTS: PD patients exhibited prolonged swing (p=0.002) and stance times (p < 0.001) and lower speed values (p < 0.001) compared to controls. This was consistent in all age groups, except for the one between 76 and 88 years old, in which the controls were slower and had longer swing and stance times. These results were statically significant for the group from 60 to 66 years. CONCLUSION: Gait speed, swing, and stance times are useful for differentiating PD patients from controls. Quantitative gait parameters measured by an RGB-D camera can complement clinical assessment of PD patients. The analysis of these spatiotemporal variables should consider the age of the subject.
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spelling pubmed-65953952019-07-16 Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera Muñoz Ospina, Beatriz Valderrama Chaparro, Jaime Andrés Arango Paredes, Juan David Castaño Pino, Yor Jaggy Navarro, Andrés Orozco, Jorge Luis Parkinsons Dis Research Article BACKGROUND: Gait alterations are hallmarks for the diagnosis and follow-up of patients with Parkinson's disease (PD). In normal conditions, age could affect gait dynamics. Although it is known that objective assessment of gait is a valuable tool for diagnosis and follow-up of patients with PD, only few studies evaluate the effect of aging on the gait pattern of patients with PD. OBJECTIVE: The purpose of this study was to assess differences in gait dynamics between PD patients and healthy subjects and to investigate the effects of aging on these differences using a low-cost RGB-D depth-sensing camera. METHODS: 30 PD patients and 30 age-matched controls were recruited. Descriptive analysis was used for clinical variables, and Spearman's rank correlation was used to correlate age and gait variables. The sample was distributed in age groups; then, Mann–Whitney U test was used for comparison of gait variables between groups. RESULTS: PD patients exhibited prolonged swing (p=0.002) and stance times (p < 0.001) and lower speed values (p < 0.001) compared to controls. This was consistent in all age groups, except for the one between 76 and 88 years old, in which the controls were slower and had longer swing and stance times. These results were statically significant for the group from 60 to 66 years. CONCLUSION: Gait speed, swing, and stance times are useful for differentiating PD patients from controls. Quantitative gait parameters measured by an RGB-D camera can complement clinical assessment of PD patients. The analysis of these spatiotemporal variables should consider the age of the subject. Hindawi 2019-06-13 /pmc/articles/PMC6595395/ /pubmed/31312423 http://dx.doi.org/10.1155/2019/5050182 Text en Copyright © 2019 Beatriz Muñoz Ospina et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Muñoz Ospina, Beatriz
Valderrama Chaparro, Jaime Andrés
Arango Paredes, Juan David
Castaño Pino, Yor Jaggy
Navarro, Andrés
Orozco, Jorge Luis
Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title_full Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title_fullStr Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title_full_unstemmed Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title_short Age Matters: Objective Gait Assessment in Early Parkinson's Disease Using an RGB-D Camera
title_sort age matters: objective gait assessment in early parkinson's disease using an rgb-d camera
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595395/
https://www.ncbi.nlm.nih.gov/pubmed/31312423
http://dx.doi.org/10.1155/2019/5050182
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