Interferon Regulatory Factor 3 Deficiency Induces Age-Related Alterations of the Retina in Young and Old Mice

Age-related changes in visual function and retina structure are very common in aged animals, but the underlying mechanisms of these changes remain unclear. Here we report that the expression of interferon regulatory factor 3 (IRF3), a critical immune regulatory factor, is dramatically down-regulated...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Zhu, Jingyi, Chen, Xianjun, Jie-Qiong, Zhang, Li, Xue, Luo, Linlin, Huang, Huang, Liu, Wenyi, Zhou, Xinyuan, Yan, Jun, Lin, Sen, Ye, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596281/
https://www.ncbi.nlm.nih.gov/pubmed/31281243
http://dx.doi.org/10.3389/fncel.2019.00272

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