Mice engineered to mimic a common Val66Met polymorphism in the BDNF gene show greater sensitivity to reversal in environmental contingencies

• A common human polymorphism in the gene that encodes brain derived neurotrophic factor (BDNF), Val66Met, is considered a marker of vulnerability for mental health issues and has been associated with cognitive impairment. An alternate framework has been proposed in which “risk alleles” are reinterp...

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Detalles Bibliográficos
Autores principales: Vandenberg, Angela, Lin, Wan Chen, Tai, Lung-Hao, Ron, Dorit, Wilbrecht, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596311/
https://www.ncbi.nlm.nih.gov/pubmed/29909248
http://dx.doi.org/10.1016/j.dcn.2018.05.009

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