Cargando…

Enterotoxigenic Escherichia coli Interferes FATP4-Dependent Long-Chain Fatty Acid Uptake of Intestinal Epithelial Enterocytes via Phosphorylation of ERK1/2-PPARγ Pathway

Sufficient fatty acid (FA) uptake from jejunal lumen is closely associated with pediatric growth. Enterotoxigenic Escherichia coli (ETEC), which poses a big threat to young mammals’ health, is also targeted on the jejunum, however, the effects on FA uptake is not understood yet. To explore the impac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhi, Liu, Heyuan, Xu, Bocheng, Wang, Yizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596317/ https://www.ncbi.nlm.nih.gov/pubmed/31281267 http://dx.doi.org/10.3389/fphys.2019.00798

Ejemplares similares

PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression
por: Ye, Guozhu, et al.
Publicado: (2019)

LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages
por: Liu, Heyuan, et al.
Publicado: (2019)

Overexpression of CD36 and Acyl-CoA Synthetases FATP2, FATP4 and ACSL1 Increases Fatty Acid Uptake in Human Hepatoma Cells
por: Krammer, Julia, et al.
Publicado: (2011)

Long-Chain Polyunsaturated Fatty Acids Attenuate Enterotoxigenic Escherichia coli K88-Induced Intestinal Barrier Damage via PPARγ Regulation in IPEC-J2 Cells
por: Zheng, Rui, et al.
Publicado: (2022)

Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down‐regulation of phosphorylation of PPARγ in 3T3‐L1 cells
por: Liu, Lei, et al.
Publicado: (2017)

Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 Increase the Cellular Fatty Acid Uptake of 3T3-L1 Adipocytes but Are Localized on Intracellular Membranes
por: Zhan, Tianzuo, et al.
Publicado: (2012)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Computational Modeling of Glucose Uptake in the Enterocyte
por: Afshar, Nima, et al.
Publicado: (2019)

Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARγ expression and phosphorylation
por: Wu, Ling, et al.
Publicado: (2010)

The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells
por: Bolden, Adrienne, et al.
Publicado: (2012)

Obesity-linked phosphorylation of PPARγ by cdk5 is a direct target of the anti-diabetic PPARγ ligands
por: Choi, Jang Hyun, et al.
Publicado: (2010)

An Erk/Cdk5 axis controls the diabetogenic actions of PPARγ
por: Banks, Alexander S., et al.
Publicado: (2014)

IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes
por: Luo, Min, et al.
Publicado: (2017)

The Effect of FATP1 on Adipocyte Differentiation in Qinchuan Beef Cattle
por: Liu, Xuchun, et al.
Publicado: (2021)

PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment
por: Dias, Marieli Mariano Gonçalves, et al.
Publicado: (2020)

Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes
por: Perez, Vincent M., et al.
Publicado: (2020)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease
por: Ran, Li-Sha, et al.
Publicado: (2022)

Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition
por: Capelli, Davide, et al.
Publicado: (2023)

The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes
por: Frkic, Rebecca L., et al.
Publicado: (2021)

dFatp regulates nutrient distribution and long-term physiology in Drosophila
por: Sujkowski, Alyson, et al.
Publicado: (2012)

Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide
por: Hu, Zhenhua, et al.
Publicado: (2020)

c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs
por: González-Loyola, Alejandra, et al.
Publicado: (2022)

Emerging Themes in the Molecular Pathogenesis of Enterotoxigenic Escherichia coli
por: Fleckenstein, James M, et al.
Publicado: (2021)

Laquinimod Prevents Adipogenesis and Obesity by Down-Regulating PPAR-γ and C/EBPα through Activating AMPK
por: Wang, Guang, et al.
Publicado: (2020)

Vibrio parahaemolyticus, enterotoxigenic Escherichia coli, enterohemorrhagic Escherichia coli and Vibrio cholerae
por: TAKEDA, Yoshifumi
Publicado: (2011)

Escherichia coli HS and Enterotoxigenic Escherichia coli Hinder Stress Granule Assembly
por: Velásquez, Felipe, et al.
Publicado: (2020)

Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina
por: Van Den Brink, Daan M., et al.
Publicado: (2018)

Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis
por: Chen, Yuting, et al.
Publicado: (2020)

PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium
por: Duszka, Kalina, et al.
Publicado: (2017)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

Computational Modelling of Glucose Uptake by SGLT1 and Apical GLUT2 in the Enterocyte
por: Afshar, Nima, et al.
Publicado: (2021)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

Nucleotide sequence analysis of the enterotoxigenic Escherichia coli Ent plasmid
por: Ochi, Sadayuki, et al.
Publicado: (2009)

Enterotoxigenic Escherichia coli Multilocus Sequence Types in Guatemala and Mexico
por: Nicklasson, Matilda, et al.
Publicado: (2010)

Enterotoxigenic Escherichia coli and Vibrio cholerae Diarrhea, Bangladesh, 2004
por: Qadri, Firdausi, et al.
Publicado: (2005)

From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development
por: Svennerholm, Ann-Mari
Publicado: (2011)

Complete Genome Sequence of Enterotoxigenic Escherichia coli Siphophage Seurat
por: Doan, Dung P., et al.
Publicado: (2015)

Complete Genome Sequence of Enterotoxigenic Escherichia coli Myophage Murica
por: Wilder, Joseph N., et al.
Publicado: (2015)

HldE Is Important for Virulence Phenotypes in Enterotoxigenic Escherichia coli
por: Maigaard Hermansen, Grith M., et al.
Publicado: (2018)

Genome Sequence of Enterotoxigenic Escherichia coli Strain FMU073332
por: Saldaña-Ahuactzi, Zeus, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bpemrn39vmf3bik6hbuumso3st