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Structural Basis of IL-1 Family Cytokine Signaling
Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli. The basic mechanism of signal initiation is a stepwise process in which an agonist cytokine binds its cognate receptor. Tog...
Autores principales: | Fields, James K., Günther, Sebastian, Sundberg, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596353/ https://www.ncbi.nlm.nih.gov/pubmed/31281320 http://dx.doi.org/10.3389/fimmu.2019.01412 |
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