Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling

BACKGROUND: One of the principles underpinning our understanding of ageing is that DNA damage induces a stress response that shifts cellular resources from growth towards maintenance. A contrasting and seemingly irreconcilable view is that prompting growth of, for example, skeletal muscle confers sy...

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Detalles Bibliográficos
Autores principales: Alyodawi, Khalid, Vermeij, Wilbert P., Omairi, Saleh, Kretz, Oliver, Hopkinson, Mark, Solagna, Francesca, Joch, Barbara, Brandt, Renata M.C., Barnhoorn, Sander, van Vliet, Nicole, Ridwan, Yanto, Essers, Jeroen, Mitchell, Robert, Morash, Taryn, Pasternack, Arja, Ritvos, Olli, Matsakas, Antonios, Collins‐Hooper, Henry, Huber, Tobias B., Hoeijmakers, Jan H.J., Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596402/
https://www.ncbi.nlm.nih.gov/pubmed/30916493
http://dx.doi.org/10.1002/jcsm.12404

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