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An equivariant Bayesian convolutional network predicts recombination hotspots and accurately resolves binding motifs

MOTIVATION: Convolutional neural networks (CNNs) have been tremendously successful in many contexts, particularly where training data are abundant and signal-to-noise ratios are large. However, when predicting noisily observed phenotypes from DNA sequence, each training instance is only weakly infor...

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Detalles Bibliográficos
Autores principales: Brown, Richard C, Lunter, Gerton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596897/
https://www.ncbi.nlm.nih.gov/pubmed/30481258
http://dx.doi.org/10.1093/bioinformatics/bty964