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Cellular Trafficking of Sn-2 Phosphatidylcholine Prodrugs Studied with Fluorescence Lifetime Imaging and Super-resolution Microscopy

While the in vivo efficacy of Sn-2 phosphatidylcholine prodrugs incorporated into targeted, non-pegylated lipid-encapsulated nanoparticles was demonstrated in prior preclinical studies, the microscopic details of cell prodrug internalization and trafficking events are unknown. Classic fluorescence m...

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Detalles Bibliográficos
Autores principales: Maji, Dolonchampa, Lu, Jin, Sarder, Pinaki, Schmieder, Anne H., Cui, Grace, Yang, Xiaoxia, Pan, Dipanjan, Lew, Matthew D., Achilefu, Samuel, Lanza, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597004/
https://www.ncbi.nlm.nih.gov/pubmed/31249994
http://dx.doi.org/10.33218/prnano1(2).180724.1